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Similarly, according to a fascinating new theory from evolutionary medicine called the "rewards deficiency syndrome" some people, due to genetic defects, do not produce sufficient neurotransmitters, particularly dopamine, in response to pleasure drives for eating, love and reproduction. As a result they seek dopamine release and sensations of pleasure via junk foods and drugs such as sugar, alcohol, cocaine, methamphetamine, heroin, nicotine, marijuana, and by compulsive activities such as gambling, eating, sex, and risk taking behaviors. Other researchers support this theory, noting low levels of serotonin are linked to ADHD and are associated with increased aggression in humans and other animals.
Following the rewards deficiency syndrome theory and the fact that stimulant medications act primarily by altering levels of dopamine, numerous genetic studies of ADHD have looked at defects in genes that control dopamine receptors. One allele of the dopamine D2 receptor gene is associated with alcoholism, drug abuse, smoking, obesity, compulsive gambling, and several personality traits. Other researchers support these findings, suggesting that defects in dopamine receptors genes are implicated in ADHD.
Driven to Distraction
A final take on ADHD, promoted by high tech magazines such as Wired, accepts it as the natural outcome of our wired economy. The disorder is said to produce "brilliant" and creative entrepreneurs who are well adapted to the information age and are skilled "multi-taskers." The ADHD personality fits right into life in the information age and people with ADHD are just "scanning" their environment like an efficient machine. They start books but don't finish them and require constant reminders, clicking and surfing their way thru life, showing up late and going off on long tangents in conversations or interrupting others. But when something finally does get their attention they enter a highly focused state and stay up all night in an explosion of productivity. They don't lack attention as much as control over it and often must turn to self-employment and forgo relationships as a result of the disorder. Some researchers suggest people with ADHD have slow brain processing speeds and thus perceive time as moving more quickly and have difficulty processing the glut of new information all around them.
Conventional Diagnosis
Despite or because of, the cultural construction of ADHD, it is being diagnosed at increasingly high rates. According to the American Psychiatric Association's Diagnostic & Statistical Manual-IV-TR, 3-7% of children currently suffer from ADHD, with boys outnumbering girls 3 to 1. In addition, a recent study finds that 1 to 6% of adults meet formal diagnostic criteria for ADHD. Many children who have been sexually abused show symptoms that can often be confused with ADHD. For example, one study found that physical or sexual maltreatment and post-traumatic stress disorder (PTSD) (hyperarousal/hypervigilance) symptoms overlapped with those of ADHD. ADHD is also frequently confused with bi-polar disorder. Other bizarre and confusing diagnostic features of ADHD include too much smiling or too large a smile, visual attention loss, fidgeting, poor reading skills, disorganization, and frequent interruption.
Conventional Treatments
Conventional treatments for ADHD include powerful stimulant medications such as Ritalin (methylphenidate) and Dexedrine (dextroamphetamine). These seem to work by suppressing all spontaneous behavior, and chimps on these drugs cease any self-generated behavior while in humans, play, socializing and exploration all decline. Unfortunately, stimulant drugs come with some severe side effects including insomnia, anxiety, social withdrawal, fatigue, passivity, emotional flatness, depression, headaches, facial tics, stereotypical behavior, and obsessive-compulsive behavior, growth impairment, increased blood pressure, and liver damage in some cases. Antidepressants, sedatives, and mood stabilizers are then prescribed to control emotional disturbances caused by initial stimulant medication. Drug addiction is also a problem since these treatments act in a similar manner to many recreational drugs. For example, nicotine promotes the release of dopamine and has been shown to improve attention in adults with ADHD. Non-stimulant drugs which may be safe and more effective are under development such as ABT-418, a nicotine analogue.
Anthropological Treatment
An anthropological approach to ADHD is a bit more radical and involves "unplugging" the patient from the source of the disorder: the cultural matrix that triggers and maintains and defines them as diseased. Meditation, retreats to wilderness areas, wild foods, herbs and exercise are all prescribed. Small group interaction and natural cycles of day and night are also required.
It is key to eliminate non-adaptive foods (foods which human agriculture has genetically modified most extensively recently and thus have become most foreign to our physiology) including wheat, sugar, oranges, soy, milk, corn, food dyes and other artificial additives, and eggs. Sugar causes reactive hypoglycemia and rapidly raises adrenaline. Children with ADHD show abnormal cortisol patterns which often occur in people with problems metabolizing carbohydrates.
Modern foods are notoriously low in certain compounds which are considered to be important for avoiding ADHD. Essential fatty acids are a good example and some researchers go so far as to claim that ADHD might be EFA deficiency in disguise since blood levels of EFAs (AA and DHA) were lower than usual in people with ADHD. ADHD, dyslexia, dyspraxia and autism are now considered "phospholipid disorders" since phospholipids are so important in these conditions.
Wild foods, most acceptably herbs in the current US healthcare system, are loaded with compounds often later isolated as drugs that act powerfully in the human body in ways that no domesticated food can. Current research on ethnobotanicals for ADHD and other neurological disorders is focusing on their action against what is termed "hypercoagulation' in which excess coagulation of the blood leads to hypoxia or low oxygen and death in tissues. Effective herbs are curcumin (turmeric extract), ginger, ginseng, and ginkgo. Stress reducing herbs like passion flower, valerian or lemon balm are recommended. Algae is sometimes used for its detoxifying effect since ADHD is attributed to exposure to heavy metals, petrochemicals and other toxins by some researchers. Symptoms of heavy metal and chemical poisoning are similar to those of ADHD. Since ADHD is also attributed to elevated thyroid hormone, certain herbs that lower thyroid levels are sometimes used. There is hardly time to review all the natural products used for this disorder here so please see the excellent compilation of protocols available on the Life Extension Foundation website http://www.lef.org
Faraone, Stephen 2001 The Genetics of ADHD. Psychiatric Grand Rounds, University of Massachusetts Medical School (April, 2001)
Tim Batchelder, BA is a medical anthropologist and can be reached at tim@anthrocode.com For links, references, articles, feedback, and other stimulating reading please see http:// www.anthrocode.com
Tim Batchelder, BA www.anthrocode.com * timbatchelder@hotmail.com
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